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The mission of the Chordoma Foundation is to rapidly develop effective treatments and ultimately a cure for chordoma, while improving the diagnosis, treatment, and quality of life for people affected by this devastating bone cancer of the skull and spine. Currently, no effective chemotherapies exist, and a lack of valid chordoma cell lines is preventing the development of new treatments. The Chordoma Foundation needs your help to assemble a panel of well-characterized chordoma cell lines that can be shared with researchers and companies across the world. Cell lines in this panel should represent the diverse set of clinical manifestations of the disease, including chordomas of the skull-base and spine from primary, recurrent, and metastatic tumors from adult and pediatric patients. The Chordoma Foundation will award a $10,000 prize for each cell line that is determined by the Chordoma Foundation to meet the requirements listed in the Detailed Description and Technical Requirements. The prize will be made as an unrestricted award to your institution to be used for scientific and educational application. In return for the award, Solvers and their institutions are expected to grant rights to the Chordoma Foundation to freely use, store and distribute the cell lines for all research and development purposes. The terms of the grant of rights are included in the Challenge-Specific Agreement for this Challenge. If required by your institution, the Chordoma Foundation also will work with you to execute an appropriate material transfer agreement to govern sharing of your cell line. Discover how to submit your cell lines in the Detailed Description and Technical Requirements for the Challenge.