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Main Project Information
Presented By Princeton University
Goal Map 3D Neurons and Discover Neuroscience Secrets
Task Solve 3D puzzles to decipher neuronal synaptic connections.
Where Online only

Based in the Seung Computational Neuroscience Lab at Princeton University, Eyewire investigators are solving the mysteries of the brain with the help of the public.  Over 225,000 people around the world have played what has been called a “3D neuroscience coloring book” — a puzzle game anyone can play without having any knowledge or experience in the field of neuroscience. 

Eyewire researchers aim to eventually map the human brain, but for now they are starting with the retina.  Players map the connections between retinal neurons, helping researchers understand how neurons process information.  Players have already helped researchers understand how a mammal can detect motion, which has remained a mystery — until now.  Eyewire researchers hope their work can lead to advances in blindness therapies, the development of retinal prosthestics, and other benefits.

How to Join

Go to You'll be asked to register (just pick a username and password) and then you'll go through an instructive and engaging tutorial. After completing the tutorial you'll start playing, earning points, and helping us with our goal: the connectome.

To learn more about what's going on behind the scenes,you can go to and to learn more about the science of the retina go to

EyeWire has an initiative called EyeLearn that is aiming to create a global community of student citizen scientists.

Social Media
Ideal Age Group Elementary school (6 - 10 years), Middle school (11 - 13 years), High school (14 - 17 years), College, Graduate students, Adults, Families, Seniors
Ideal Frequency Every few days
Average Time An hour or so
Spend the Time indoors
Type of Activity Exclusively online, At school, At night, At home
Training Materials
Class Materials
Media Mentions
and Publications
Tags 3d, at home, autism, biology, biomedical, brain, brain abnormality, brain map, connectome, eyewire, game, neuron, neuroscience, puzzle, retina, retina structure, rwjf
Project Updated 05/23/2018